Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing CTX-M extended-spectrum beta-lactamases
- PMID: 19124661
- PMCID: PMC2650586
- DOI: 10.1128/AAC.01519-08
Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing CTX-M extended-spectrum beta-lactamases
Abstract
Effective therapeutic options are needed for community-onset urinary tract infections due to Escherichia coli strains that produce CTX-M extended-spectrum beta-lactamases. We examined 46 urinary isolates producing CTX-M against several oral or long-acting parenteral antimicrobial agents. Approximately 90% were susceptible to fosfomycin and to a combination of cefdinir plus amoxicillin-clavulanate. All were susceptible to ertapenem.
References
-
- Alhambra, A., J. A. Cuadros, J. Cacho, J. L. Gómez-Garcés, and J. I. Alós. 2004. In vitro susceptibility of recent antibiotic-resistant urinary pathogens to ertapenem and 12 other antibiotics. J. Antimicrob. Chemother. 53:1090-1094. - PubMed
-
- Bonsu, B. K., L. Shuler, L. Sawicki, P. Dorst, and D. M. Cohen. 2006. Susceptibility of recent bacterial isolates to cefdinir and selected antibiotics among children with urinary tract infections. Acad. Emerg. Med. 13:76-81. - PubMed
-
- Calbo, E., V. Romaní, M. Xercavins, L. Gómez, C. G. Vidal, S. Quintana, J. Vila, and J. Garau. 2006. Risk factors for community-onset urinary tract infections due to Escherichia coli harbouring extended-spectrum β-lactamases. J. Antimicrob. Chemother. 57:780-783. - PubMed
-
- Clinical and Laboratory Standards Institute. 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A7. Clinical and Laboratory Standards Institute, Wayne, PA.
-
- Clinical and Laboratory Standards Institute. 2008. Performance standards for antimicrobial susceptibility testing. Supplement M100-S18. Clinical and Laboratory Standards Institute, Wayne, PA.
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