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Case Reports
. 2009 Jan 6;180(1):72-4.
doi: 10.1503/cmaj.080572.

Painful swelling in the thigh: diabetic muscle infarction

Ami Schattner  1 , Taiba Zornitzki, Meital Adi, Joshua Friedman
Affiliations
Case Reports

Painful swelling in the thigh: diabetic muscle infarction

Ami Schattner et al. CMAJ. .
No abstract available

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Figures

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Figure 1: Magnetic resonance imaging of the patient's thighs. A: T1-weighted images showing swelling and hypointensity (arrow) of the involved muscle. B: T2-weighted images showing diffuse, heterogeneous signal in the involved muscle (arrow), suggesting edema. C: A focal area of heterogeneously enhanced mass (arrow) with peripheral enhancement was visible after adminstration of gadolinium.
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Figure 2: Magnetic resonance imaging of the patient's thigh. A: Coronal image showing diffuse, heterogeneous, intense signal of the involved muscle (arrow), which suggests edema. B: Sagittal image showing a heterogeneously enhanced mass (arrow) with peripheral enhancement after adminstration of gadolinium.
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Figure 3: Muscle biopsy showing ischemic skeletal muscle fibres with areas of necrosis (black arrow), reparative changes with myofibre regeneration (white arrow), signs of fibrosis, fat necrosis and chronic inflammation. Atherosclerotic changes are seen in medium-sized vessels and fibrin thrombi are seen in the small vessels (hematoxylin–eosin stain, original magnification × 40).
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References

    1. Kapur S, Brunet JA, McKendry RJ. Diabetic muscle infarction: case report and review. J Rheumatol 2004;31:190-4. - PubMed
    1. Trujillo-Santos AJ. Diabetic muscle infarction. An underdiagnosed complication of long-standing diabetes. Diabetes Care 2003;26:211-5. - PubMed
    1. Kattapuram TM, Suri R, Rosol MS, et al. Idiopathic and diabetic skeletal muscle necrosis: evaluation by magnetic resonance imaging. Skeletal Radiol 2005;34:203-9. - PubMed
    1. Kapur S, McKendry RJ. Treatment and outcomes of diabetic muscle infarction. J Clin Rheumatol 2005;11:8-12. - PubMed

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