Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
- PMID: 19127977
- PMCID: PMC2613424
- DOI: 10.1371/journal.pmed.1000015
Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?
Abstract
Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five.
Conflict of interest statement
Comment on
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Time to move from presumptive malaria treatment to laboratory-confirmed diagnosis and treatment in African children with fever.PLoS Med. 2009 Jan 6;6(1):e252. doi: 10.1371/journal.pmed.0050252. PLoS Med. 2009. PMID: 19127974 Free PMC article.
References
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- World Health Organization. World Malaria Report. 2008. Available: http://www.who.int/malaria/wmr2008/. Accessed 17 November 2008.
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