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. 1991 Sep;68(3):258-62.
doi: 10.1111/j.1464-410x.1991.tb15318.x.

Neuro-endocrine cells--a new prognostic parameter in prostate cancer

R J Cohen  1 , G Glezerson, Z Haffejee
Affiliations

Neuro-endocrine cells--a new prognostic parameter in prostate cancer

R J Cohen et al. Br J Urol. 1991 Sep.

Abstract

Neuro-endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro-endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro-endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.

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