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. 2009 May;31(5):583-92.
doi: 10.1002/hed.20993.

Endoscopic laser surgery of early glottic cancer: involvement of the anterior commissure

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Endoscopic laser surgery of early glottic cancer: involvement of the anterior commissure

Ralph M W Rödel et al. Head Neck. 2009 May.

Abstract

Background: Early glottic cancer can be cured with transoral laser resection, but in cases with anterior commissure involvement, there is still controversy concerning the best treatment modality.

Methods: The impact of anterior commissure involvement on local control was analyzed in a retrospective review of 444 patients with early glottic cancer (pT1a-pT2a) treated between 1986 and 2004 with transoral laser microsurgical resection.

Results: The anterior commissure was involved in 153 cases; the 5-year local control rate with and without anterior commissure involvement was 73% versus 89% for T1a and 68% versus 86% for T1b tumors. For T2a lesions, the 5-year local control rate was 76%, irrespective of anterior commissure involvement.

Conclusion: In early glottic cancer treated by transoral laser microsurgery, a decrease in local control is evident in case of anterior commissure involvement for T1a and T1b but not for T2a tumors.

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