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. 2009 Apr;53(4):1648-51.
doi: 10.1128/AAC.01148-07. Epub 2009 Jan 12.

Voriconazole use for endemic fungal infections

Alison Freifeld  1 , Laurie Proia, David Andes, Larry M Baddour, Janis Blair, Brad Spellberg, Sandra Arnold, Arnold Lentnek, L Joseph Wheat
Affiliations

Voriconazole use for endemic fungal infections

Alison Freifeld et al. Antimicrob Agents Chemother. 2009 Apr.

Abstract

In a retrospective review of 24 patients with histoplasmosis, blastomycosis, or coccidioidomycosis treated with voriconazole (most for salvage therapy), the outcome was favorable (improved or stable) for 22 (95.8%) within 2 months of starting voriconazole and for 20 (83.3%) at the last follow-up. Prospective studies are required to determine its role in the treatment of endemic mycoses.

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