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Case Reports
. 2009;71(2):78-86.
doi: 10.1159/000189783. Epub 2009 Jan 10.

Ménière's disease is a viral neuropathy

Richard R Gacek  1
Affiliations
Case Reports

Ménière's disease is a viral neuropathy

Richard R Gacek. ORL J Otorhinolaryngol Relat Spec. 2009.

Abstract

Morphological and clinical evidence supports a viral neuropathy in Ménière's disease (MD). Quantitative examination of 11 sectioned temporal bones (TBs) from 8 patients with a history of MD revealed a significant loss of vestibular ganglion cells in both the endolymph hydropic (EH) and non-EH ears. Transmission electron microscopy of vestibular ganglion cells excised from a patient with MD revealed viral particles enclosed in transport vesicles. Antiviral treatment controlled vertigo in 73 of 86 patients with vestibular neuronitis (85%) and 32 of 35 patients with MD (91%).

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