Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009;48(7):1296-9.
doi: 10.1002/anie.200804310.

Palladium-catalyzed substitution of allylic fluorides

Amaruka Hazari  1 , Véronique Gouverneur, John M Brown
Affiliations

Palladium-catalyzed substitution of allylic fluorides

Amaruka Hazari et al. Angew Chem Int Ed Engl. 2009.

Abstract

As unusual substrates for the Tsuji-Trost allylation reaction, allylic fluorides are responsive to palladium-catalyzed substitution. Their activity towards this reaction fits in the series OCO(2)Me>OBz>>F>>OAc. The classic stereoretention mechanism that involves sequential inversions does not operate in this case. Several distinct cases are considered.

PubMed Disclaimer

LinkOut - more resources