Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Feb;174(2):357-60.
doi: 10.2353/ajpath.2009.081029. Epub 2009 Jan 15.

The translational basis of human cutaneous photoaging: on models, methods, and meaning

Alvaro C Laga  1 , George F Murphy
Affiliations
Review

The translational basis of human cutaneous photoaging: on models, methods, and meaning

Alvaro C Laga et al. Am J Pathol. 2009 Feb.

Abstract

This Commentary reports on the effects of photoaging in an experimental model of ultraviolet radiation B on human skin.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Comparison between youthful skin (regarded by society as normal), skin from an older individual showing loss of rete ridges and thinning of dermal collagen bundles, and photodamaged skin with superimposed aggregates of amorphous, pale blue-gray elastin in the superficial dermis. H&E stain. Original magnifications, ×200.
See this image and copyright information in PMC

Comment on

References

    1. Kligman LH, Kligman AM. The nature of photoageing: its prevention and repair. Photodermatology. 1986;3:215–227. - PubMed
    1. Choi CM, Berson DS. Cosmeceuticals. Semin Cutan Med Surg. 2006;25:163–168. - PubMed
    1. Yaar M, Eller MS, Gilchrest BA. Fifty years of skin aging. J Invest Dermatol Symp Proc. 2002;7:51–58. - PubMed
    1. Kligman AM, Zheng P, Lavker RM. The anatomy and pathogenesis of wrinkles. Br J Dermatol. 1985;113:37–42. - PubMed
    1. Kurban RS, Bhawan J. Histologic changes in skin associated with aging. J Dermatol Surg Oncol. 1990;16:908–914. - PubMed