Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Dec;87(5):459-66.
doi: 10.1007/s12041-008-0068-5.

The electroretinogram as a method for studying circadian rhythms in the mammalian retina

Morven A Cameron  1 , Alun R Barnard, Robert J Lucas
Affiliations
Review

The electroretinogram as a method for studying circadian rhythms in the mammalian retina

Morven A Cameron et al. J Genet. 2008 Dec.

Abstract

Circadian clocks are thought to regulate retinal physiology in anticipation of the large variation in environmental irradiance associated with the earth's rotation upon its axis. In this review we discuss some of the rhythmic events that occur in the mammalian retina, and their consequences for retinal physiology. We also review methods of tracing retinal rhythmicity in vivo and highlight the electroretinogram (ERG) as a useful technique in this field. Principally, we discuss how this technique can be used as a quick and noninvasive way of assessing physiological changes that occur in the retina over the course of the day. We highlight some important recent findings facilitated by this approach and discuss its strengths and limitations.

PubMed Disclaimer

References

    1. Science. 1996 Apr 19;272(5260):419-21 - PubMed
    1. Vision Res. 2003 Sep;43(19):2089-99 - PubMed
    1. Invest Ophthalmol Vis Sci. 1983 Sep;24(9):1203-10 - PubMed
    1. Neuron. 2008 Sep 11;59(5):790-801 - PubMed
    1. J Neurosci. 1992 Dec;12(12):4911-22 - PubMed