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. 2009;48(9):1546-8.
doi: 10.1002/anie.200805237.

Catalytic C-F activation and hydrodefluorination of fluoroalkyl groups

Gregor Meier  1 , Thomas Braun
Affiliations

Catalytic C-F activation and hydrodefluorination of fluoroalkyl groups

Gregor Meier et al. Angew Chem Int Ed Engl. 2009.

Abstract

A powerful fluoride trap: The extremely Lewis acidic silyl cation [Et(3)Si](+) is an active catalyst for the hydrodefluorination of fluoroalkyl groups at room temperature (see example). The carborane anion [CHB(11)H(5)Cl(6)](-) plays an essential role in the catalytic cycle as a weakly coordinating anion that stabilizes cationic intermediates.

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