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Review
. 2009 Apr;18(4):449-64.
doi: 10.1007/s00586-008-0878-4. Epub 2009 Jan 17.

Bone graft substitutes in anterior cervical discectomy and fusion

Anthony M T Chau  1 , Ralph J Mobbs
Affiliations
Review

Bone graft substitutes in anterior cervical discectomy and fusion

Anthony M T Chau et al. Eur Spine J. 2009 Apr.

Abstract

Anterior cervical discectomy with fusion is a common surgical procedure for patients suffering pain and/or neurological deficits and unresponsive to conservative management. For decades, autologous bone grafted from the iliac crest has been used as a substrate for cervical arthrodesis. However patient dissatisfaction with donor site morbidity has led to the search for alternative techniques. We present a literature review examining the progress of available grafting options as assessed in human clinical trials, considering allograft-based, synthetic, factor- and cell-based technologies.

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Figures

Fig. 1
Fig. 1
Historical perspective of autogenous bone graft techniques. a Cloward dowel, b Smith-Robinson horseshoe, c Simmons-Bhalla keystone, d Bailey-Badgley onlay strut
See this image and copyright information in PMC

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