Idiopathic inflammatory bowel disease in cats. Rational treatment selection
- PMID: 19154973
- PMCID: PMC11135483
- DOI: 10.1016/j.jfms.2008.11.011
Idiopathic inflammatory bowel disease in cats. Rational treatment selection
Abstract
Practical relevance Inflammatory bowel disease (IBD) is a common diagnosis in cats with chronic gastrointestinal signs. Its management presents clinical challenges, not least because rational therapy relies on a definitive diagnosis, and current understanding of the underlying pathogenesis has, to date, limited the development of specific therapies. The mainstays of treatment remain dietary manipulation and immunosuppressive therapy, but treatment failures are not uncommon. A logical clinical approach is important and there are a number of alternative or adjunctive treatments that can prove useful in refractory cases.
Evidence base This article draws on data from clinical trials in humans, in vitro studies, prospective and retrospective studies in cats with naturally occurring IBD, and clinical experience to discuss the work-up and treatment selection for cats with idiopathic IBD.
Patient group IBD affects young adult to geriatric cats of both sexes.
Audience Companion animal and feline practitioners are at the front line when it comes to managing these often challenging cases.
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References
-
- Waly NE,Stokes CR,Gruffydd-Jones TJ,Day MJ.Immune cell populations in the duodenal mucosa of cats with inflammatory bowel disease.J Vet Intern Med. 2004;18:816-25 - PubMed
-
- Janeczko S,Atwater D,Bogel E, et al.The relationship of mucosal bacteria to duodenal histopathology, cytokine mRNA, and clinical disease activity in cats with inflammatory bowel disease.Vet Microbiol. 2008;128:178-93 - PubMed
-
- Evans SE,Bonczynski JJ,Broussard JD,Han E,Baer KE.Comparison of endoscopic and full-thickness biopsy specimens for diagnosis of inflammatory bowel disease and alimentary tract lymphoma in cats.J Am Vet Med Assoc. 2006;229:1447-50 - PubMed
-
- Penninck D,Smyers B,Webster CR,Rand W,Moore AS.Diagnostic value of ultrasonography in differentiating enteritis from intestinal neoplasia in dogs.Vet Radiol Ultrasound. 2003;44:570-75 - PubMed
-
- Rivers BJ,Walter PA,Feeney DA,Johnston GR.Ultrasonographic features of intestinal adenocarcinoma in five cats.Vet Radiol Ultrasound. 1997;38:300-6 - PubMed
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