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Comment
. 2009 Jan 22;5(1):3-5.
doi: 10.1016/j.chom.2008.12.009.

The distinct roles of JAM-A in reovirus pathogenesis

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Comment

The distinct roles of JAM-A in reovirus pathogenesis

Carolyn B Coyne. Cell Host Microbe. .
Free article

Abstract

Despite their fundamental role in host defense, many components of epithelial and endothelial tight junctions serve as viral receptors. In this issue of Cell Host & Microbe, Antar et al. (2009) provide striking in vivo evidence that the broadly expressed reovirus receptor JAM-A plays a specific role in reovirus dissemination.

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