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. 2009 Feb 7;7(3):435-8.
doi: 10.1039/b819208a. Epub 2008 Dec 11.

A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger

Jon C Henrikson  1 , Ashley R Hoover, P Matthew Joyner, Robert H Cichewicz
Affiliations

A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger

Jon C Henrikson et al. Org Biomol Chem. .

Abstract

A new fungal metabolite, nygerone A (), featuring a unique 1-phenylpyridin-4(1H)-one core that had previously not been reported from any natural source, has been obtained from Aspergillus niger using a chemical epigenetics methodology.

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