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Comparative Study
. 1977 Mar;21(3):1232-5.
doi: 10.1128/JVI.21.3.1232-1235.1977.

Induction of deoxypyrimidine kinase activity in human embryonic lung cells infected with varicella-zoster virus

T Ogino, T Otsuka, M Takahashi
Comparative Study

Induction of deoxypyrimidine kinase activity in human embryonic lung cells infected with varicella-zoster virus

T Ogino et al. J Virol. 1977 Mar.

Abstract

Deoxypyrimidine kinase (deoxythymidine [TdR] kinase and deoxycytidine kinase) activity was induced in human embryonic lung cells after infection with varicella-zoster virus (VZ virus). Increased enzyme activity was also produced by using cell-associated virus as inoculum instead of cell-free virus. Anti-VZ virus serum inhibited both the appearance of cytopathic effect and the induction of enzyme activity. The induced TdR kinase activity was more thermostable than that induced by herpes simplex virus type 1. Also, the TdR kinase activity of VZ virus-infected cells was inhibited by dTTP less than in mock-infected cells and more than in herpes simplex virus type 1-infected cells.

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References

    1. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed
    1. Biken J. 1975 Mar;18(1):25-33 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1975;39 Pt 2:703-15 - PubMed
    1. Proc Soc Exp Biol Med. 1976 Feb;151(2):280-4 - PubMed
    1. Int J Cancer. 1974 Nov 15;14(5):598-610 - PubMed

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