p38delta and PKD1: kinase switches for insulin secretion
- PMID: 19167323
- DOI: 10.1016/j.cell.2009.01.005
p38delta and PKD1: kinase switches for insulin secretion
Abstract
Insufficient production of the hormone insulin by pancreatic beta cells results in diabetes. In this issue, Sumara et al. (2009) report key roles for the protein kinases p38delta and PKD1 in the regulation of insulin secretion as well as in the survival of pancreatic beta cells.
Comment on
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Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.Cell. 2009 Jan 23;136(2):235-48. doi: 10.1016/j.cell.2008.11.018. Epub 2009 Jan 8. Cell. 2009. PMID: 19135240 Free PMC article.
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