The PTP family photo album
- PMID: 19167325
- DOI: 10.1016/j.cell.2009.01.006
The PTP family photo album
Abstract
Protein tyrosine phosphatases (PTPs) are central players in many biological processes. In this issue, Barr et al. (2009) analyze 22 different PTP structures to define their common and unique features. This effort provides key insights into the regulation of PTP activity that could lead to the development of new therapeutics.
Comment on
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Large-scale structural analysis of the classical human protein tyrosine phosphatome.Cell. 2009 Jan 23;136(2):352-63. doi: 10.1016/j.cell.2008.11.038. Cell. 2009. PMID: 19167335 Free PMC article.
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