Prevalence of essential tremor in a multiethnic, community-based study in northern Manhattan, New York, N.Y
- PMID: 19169043
- PMCID: PMC2744469
- DOI: 10.1159/000195691
Prevalence of essential tremor in a multiethnic, community-based study in northern Manhattan, New York, N.Y
Abstract
Background: Our aims were to: (1) estimate the prevalence of essential tremor (ET) in a community-based study in northern Manhattan, New York, N.Y., USA; (2) compare prevalence across ethnic groups, and (3) provide prevalence estimates for the oldest old.
Methods: This study did not rely on a screening questionnaire. Rather, as part of an in-person neurological evaluation, each participant produced several handwriting samples, from which ET diagnoses were assigned.
Results: There were 1,965 participants (76.7 +/- 6.9 years, range = 66-102 years); 108 had ET [5.5%, 95% confidence interval (CI) = 4.5-6.5%]. Odds of ET were robustly associated with Hispanic ethnicity versus white ethnicity [odds ratio (OR) = 2.19, 95% CI = 1.03-4.64, p = 0.04] and age (OR = 1.14, 95% CI = 1.03-1.26, p = 0.01), i.e. with every 1 year advance in age, the odds of ET increased by 14%. Prevalence reached 21.7% among the oldest old (age > or = 95 years).
Conclusions: This study reports a significant ethnic difference in the prevalence of ET. The prevalence of ET was high overall (5.5%) and rose markedly with age so that in the oldest old, more than 1 in 5 individuals had this disease.
2009 S. Karger AG, Basel.
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Comment in
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How common is essential tremor?Neuroepidemiology. 2009;32(3):215-6. doi: 10.1159/000195692. Epub 2009 Jan 24. Neuroepidemiology. 2009. PMID: 19169044 No abstract available.
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