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Randomized Controlled Trial
. 2009 Feb;32(2):e20.
doi: 10.2337/dc08-1450.

Gabapentin extended release for the treatment of painful diabetic peripheral neuropathy: efficacy and tolerability in a double-blind, randomized, controlled clinical trial

David Sandercock, Marilou Cramer, Jacqueline Wu, Yu-Kun Chiang, Victor Biton, Michelle Heritier
Randomized Controlled Trial

Gabapentin extended release for the treatment of painful diabetic peripheral neuropathy: efficacy and tolerability in a double-blind, randomized, controlled clinical trial

David Sandercock et al. Diabetes Care. 2009 Feb.
No abstract available

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References

    1. Backonja M, Beydoun A, Edwards KR, Schwartz SL, Fonseca V, Hes M, LaMoreaux L, Garofalo E: Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial. JAMA 280:1831–1836, 1998 - PubMed
    1. Backonja M, Glanzman RL: Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trials. Clin Ther 25:81–104, 2003 - PubMed
    1. Stewart BH, Kugler AR, Thompson PR, Bockbrader HN: A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma. Pharm Res 10:276–281, 1993 - PubMed
    1. Gordi T, Hou E, Kasichayanula S, Berner B: Pharmacokinetics of gabapentin after a single day and at steady state following the administration of gastric-retentive- extended-release and immediate-release tablets: a randomized, open-label, multiple-dose, three-way crossover, exploratory study in healthy subjects. Clin Ther 30:909–916, 2008 - PubMed

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