Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?
- PMID: 19172337
- DOI: 10.1007/s12519-009-0013-6
Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing enterocolitis?
Abstract
Background: Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown.
Methods: Case report and literature review.
Results: We present preterm twins whose mother was treated with venlafaxine, a nonselective serotonin reuptake inhibitor, throughout pregnancy until delivery. The twins developed neonatal necrotizing enterocolitis.
Conclusion: The question whether there might be a correlation between maternal serotonin reuptake inhibitor therapy and neonatal necrotizing enterocolitis is discussed.
Similar articles
-
Can venlafaxine in breast milk attenuate the norepinephrine and serotonin reuptake neonatal withdrawal syndrome.J Obstet Gynaecol Can. 2006 Apr;28(4):299-301. doi: 10.1016/S1701-2163(16)32135-1. J Obstet Gynaecol Can. 2006. PMID: 16776907
-
Neurodevelopment of children following prenatal exposure to venlafaxine, selective serotonin reuptake inhibitors, or untreated maternal depression.Am J Psychiatry. 2012 Nov;169(11):1165-74. doi: 10.1176/appi.ajp.2012.11111721. Am J Psychiatry. 2012. PMID: 23128923
-
Effects of selective serotonin reuptake inhibitors and venlafaxine during pregnancy in term and preterm neonates.Pediatrics. 2007 Jan;119(1):52-9. doi: 10.1542/peds.2006-2133. Pediatrics. 2007. PMID: 17200271
-
Dose-response relationship with venlafaxine.J Clin Psychopharmacol. 1996 Jun;16(3 Suppl 2):21S-26S; discussion 26S-28S. doi: 10.1097/00004714-199606002-00005. J Clin Psychopharmacol. 1996. PMID: 8784645 Review.
-
Associations Between Maternal Depression, Antidepressant Use During Pregnancy, and Adverse Pregnancy Outcomes: An Individual Participant Data Meta-analysis.Obstet Gynecol. 2021 Oct 1;138(4):633-646. doi: 10.1097/AOG.0000000000004538. Obstet Gynecol. 2021. PMID: 34623076
Cited by
-
Antenatal Escitalopram Use and Necrotizing Enterocolitis in a Newborn: A Case Report.J Pediatr Pharmacol Ther. 2016 Nov-Dec;21(6):518-521. doi: 10.5863/1551-6776-21.6.518. J Pediatr Pharmacol Ther. 2016. PMID: 28018154 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical