doi: 10.1021/ja8087532.
A temperature-sensitive liposomal 1H CEST and 19F contrast agent for MR image-guided drug delivery
Affiliations
- PMID: 19173663
- DOI: 10.1021/ja8087532
Item in Clipboard
A temperature-sensitive liposomal 1H CEST and 19F contrast agent for MR image-guided drug delivery
J Am Chem Soc.
.
Abstract
A novel temperature-sensitive liposomal MRI contrast agent has been developed, which allows drug carrier localization using (1)H CEST with simultaneous quantification of the drug release using (19)F MR imaging in response to a local temperature increase.
Similar articles
-
Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications.Acc Chem Res. 2009 Jul 21;42(7):822-31. doi: 10.1021/ar800192p. Acc Chem Res. 2009. PMID: 19534516 Review.
-
Osmotically shrunken LIPOCEST agents: an innovative class of magnetic resonance imaging contrast media based on chemical exchange saturation transfer.Chemistry. 2009;15(6):1440-8. doi: 10.1002/chem.200801766. Chemistry. 2009. PMID: 19115311
-
Local delivery of magnetic resonance (MR) contrast agent in kidney using thermosensitive liposomes and MR imaging-guided local hyperthermia: a feasibility study in vivo.J Magn Reson Imaging. 2005 Oct;22(4):534-40. doi: 10.1002/jmri.20416. J Magn Reson Imaging. 2005. PMID: 16161081
-
Improvement in the contrast of CEST MRI via intermolecular double quantum coherences.Phys Med Biol. 2008 Jul 21;53(14):N287-96. doi: 10.1088/0031-9155/53/14/N03. Epub 2008 Jun 23. Phys Med Biol. 2008. PMID: 18574314
-
Clinical perspectives of hybrid proton-fluorine magnetic resonance imaging and spectroscopy.Invest Radiol. 2013 May;48(5):341-50. doi: 10.1097/RLI.0b013e318277528c. Invest Radiol. 2013. PMID: 23211551 Review.
Cited by
-
Elucidating the Uptake and Distribution of Nanoparticles in Solid Tumors via a Multilayered Cell Culture Model.Nanomicro Lett. 2015;7(2):127-137. doi: 10.1007/s40820-014-0025-1. Epub 2014 Dec 23. Nanomicro Lett. 2015. PMID: 30464963 Free PMC article.
-
A physiological perspective on the use of imaging to assess the in vivo delivery of therapeutics.Ann Biomed Eng. 2014 Feb;42(2):280-98. doi: 10.1007/s10439-013-0895-2. Epub 2013 Sep 10. Ann Biomed Eng. 2014. PMID: 24018607 Free PMC article. Review.
-
Applications of nanoparticles for diagnosis and therapy of cancer.Br J Radiol. 2015 Oct;88(1054):20150207. doi: 10.1259/bjr.20150207. Epub 2015 Jun 12. Br J Radiol. 2015. PMID: 25969868 Free PMC article. Review.
-
Novel non‑metal‑based contrast agents for MR imaging: Emerging approaches and clinical perspectives (Review).Int J Oncol. 2025 Aug;67(2):70. doi: 10.3892/ijo.2025.5776. Epub 2025 Jul 19. Int J Oncol. 2025. PMID: 40682851 Free PMC article. Review.
-
Design of multi-modal antenna arrays for microwave hyperthermia and 1H/1⁹F MRI monitoring of drug release.PLoS One. 2024 Oct 24;19(10):e0312343. doi: 10.1371/journal.pone.0312343. eCollection 2024. PLoS One. 2024. PMID: 39446902 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
