Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Mar 10;100(5):799-802.
doi: 10.1038/sj.bjc.6604893. Epub 2009 Jan 27.

Trends in the incidence of primary liver cancer in Central Uganda, 1960-1980 and 1991-2005

Affiliations

Trends in the incidence of primary liver cancer in Central Uganda, 1960-1980 and 1991-2005

P Ocama et al. Br J Cancer. .

Abstract

Primary liver cancer (PLC) incidence trends from Africa are unknown. Using Kampala Cancer Registry data from 1960 to 1980 and 1991 to 2005, we identified 771 PLCs. Although rates were stable among men, PLC incidence among women increased >50%. Investigations of viral hepatitis, aflatoxin, obesity, and human immunodeficiency virus (HIV) may help to explain the increasing incidence of hepatocellular carcinomas (HCCs).

PubMed Disclaimer

Figures

Figure 1
Figure 1
Age-standardised incidence rates of primary liver cancer among men (A) and women (B) overall, and stratified by age 45 years and older in Kyadondo County, Uganda: 1960–2005. Bars represent 95% confidence intervals, calculated using a natural logarithmic transformation, around each estimate.

Similar articles

Cited by

References

    1. Alpert ME, Hutt MS, Wogan GN, Davidson CS (1971) Association between aflatoxin content of food and hepatoma frequency in Uganda. Cancer 28: 253–260 - PubMed
    1. Bah E, Parkin DM, Hall AJ, Jack AD, Whittle H (2001) Cancer in the Gambia: 1988–97. Br J Cancer 84: 1207–1214 - PMC - PubMed
    1. Bica I, McGovern B, Dhar R, Stone D, McGowan K, Scheib R, Snydman DR (2001) Increasing mortality due to end-stage liver disease in patients with human immunodeficiency virus infection. Clin Infect Dis 32: 492–497 - PubMed
    1. Biggar RJ, Ortiz-Conde BA, Bagni RK, Bakaki PM, Wang CD, Engels EA, Mbulaiteye SM, Ndugwa CM (2006) Hepatitis C virus genotype 4 in Ugandan children and their mothers. Emerg Infect Dis 12: 1440–1443 - PMC - PubMed
    1. Boyle P, Parkin DM (1991) Cancer registration: principles and methods. Statistical methods for registries. IARC Sci Publ 95: 126–158 - PubMed

Publication types