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. 1991;18(5):547-50.
doi: 10.1016/0883-2897(91)90116-3.

Lipophilic 99mTc-nitride radiopharmaceuticals as potential myocardial imaging agents

J R Dilworth  1 , C M Archer, I A Latham, J D Kelly, D V Griffiths, D C York, P M Mahoney, B Higley
Affiliations

Lipophilic 99mTc-nitride radiopharmaceuticals as potential myocardial imaging agents

J R Dilworth et al. Int J Rad Appl Instrum B. 1991.

Abstract

Monocationic 99mTc-nitrido complexes of a variety of diphosphine ligands have been prepared and the in vivo distribution of such cations has been examined in Sprague-Dawley rats. These complexes show initially high myocardial uptake with subsequent wash-out in this animal model. The lack of myocardial retention can be attributed to the facile in vivo reduction of these cations.

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