Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jan 29:2:98.
doi: 10.1186/1757-1626-2-98.

Hughes-Stovin syndrome: a case report and review of the literature

Athanasios N Chalazonitis  1 , Stefanos B Lachanis, Panagiotis Mitseas, Panagiotis Argyriou, Joannie Tzovara, Petros Porfyrides, Evangelia Sotiropoulou, Nikolaos Ptohis
Affiliations

Hughes-Stovin syndrome: a case report and review of the literature

Athanasios N Chalazonitis et al. Cases J. .

Abstract

Background: Hughes-Stovin syndrome is a rare entity. The aetiology of Hughes-Stovin syndrome is still unknown and the natural course of the illness is usually fatal; however it is supposed to be a clinical variant manifestation of Behçet disease.

Case presentation: We report the case of an 18 years old, greek male patient with Hughes-Stovin syndrome, who initially presented with deep vein thrombosis. There were no findings consistent with Behçet disease and the haemoptysis was treated successfully with methylprednisolone. Pathogenesis, imaging investigation and treatment of this syndrome are also briefly discussed.

Conclusion: In young men presenting with venous thrombosis as revealed on imaging examination, with platelet count and coagulation tests within normal and hemoptysis the eventuality of Hughes-Stovin syndrome is to be considered.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Chest Contrast Enhanced-MSCT angiography axial section showing a partially thrombosed aneurysm of the right lower lobe pulmonary artery, and thrombosed segmental branch of the left lower lobe pulmonary artery.
Figure 2
Figure 2
Contrast Enhanced pulmonary MRA (coronal MIP) showing aneurysm of the right lower lobe pulmonary artery.
Figure 3
Figure 3
Axial MIP of 3D-PC MRV showing chronic thrombosis of superior sagittal and transverse sinuses (arrows).
See this image and copyright information in PMC

References

    1. Hughes JP, Stovin PGI. Segmental pulmonary artery aneurysms with peripheral venous thrombosis. Br J Dis Chest. 1959;53:19–27. doi: 10.1016/S0007-0971(59)80106-6. - DOI - PubMed
    1. Weintraub JL, DeMayo R, Haskal ZJ, Susman J. SCVIR Annual Meeting Film Panel Session: Diagnosis and Discussion of Case 1. J Vasc Interv Radiol. 2001;12:531–534. doi: 10.1016/S1051-0443(07)61897-1. - DOI - PubMed
    1. Herb S, Hetzel M, Hetzel J, Friedrich J, Weber J. An unusual case of Hughes-Stovin syndrome. Eur Respir J. 1998;11:1191–1193. doi: 10.1183/09031936.98.11051191. - DOI - PubMed
    1. Khalil A, Parrot A, Fartoukh M, Marsault C, Carette MF. Large pulmonary artery aneurysms rupture in Hughes Stovin syndrome: multidetector computed tomography pattern and endovascular treatment. Circulation. 2006;114(10):e380–381. doi: 10.1161/CIRCULATIONAHA.106.614636. - DOI - PubMed
    1. Davies JD. Behcet's syndrome with hemoptysis and pulmonary lesions. J Pathol. 1973;109(4):351–356. doi: 10.1002/path.1711090410. - DOI - PubMed

LinkOut - more resources