B cells versus T cells as primary barrier to hematopoietic engraftment in allosensitized recipients
- PMID: 19179478
- PMCID: PMC2635087
- DOI: 10.1182/blood-2008-09-177436
B cells versus T cells as primary barrier to hematopoietic engraftment in allosensitized recipients
Comment on
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Humoral immunity is the dominant barrier for allogeneic bone marrow engraftment in sensitized recipients.Blood. 2006 Nov 15;108(10):3611-9. doi: 10.1182/blood-2006-04-017467. Epub 2006 Aug 3. Blood. 2006. PMID: 16888094 Free PMC article.
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Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients.Blood. 2007 Feb 1;109(3):1307-15. doi: 10.1182/blood-2006-05-022772. Epub 2006 Oct 3. Blood. 2007. PMID: 17018854 Free PMC article.
References
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- Garver RM, Cole LJ. Passive transfer of bone marrow homotransplantation immunity with specific antisera. J Immunol. 1961;86:307–311. - PubMed
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- Storb R, Prentice RL, Thomas ED. Marrow transplantation for treatment of aplastic anemia: an analysis of factors associated with graft rejection. N Engl J Med. 1977;296:61–66. - PubMed
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