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Case Reports
. 2008 Oct;24(10):542-7.
doi: 10.1016/S1607-551X(09)70014-2.

Dual-phase 99mTc-MIBI parathyroid imaging reveals synchronous parathyroid adenoma and papillary thyroid carcinoma: a case report

Ming-Che Chang  1 , Shih-Chuan Tsai, Wan-Yu Lin
Affiliations
Case Reports

Dual-phase 99mTc-MIBI parathyroid imaging reveals synchronous parathyroid adenoma and papillary thyroid carcinoma: a case report

Ming-Che Chang et al. Kaohsiung J Med Sci. 2008 Oct.

Abstract

The possibility of a coincidental appearance of hyperparathyroidism and thyroid cancer is not often considered because of its low incidence. Here, we present a case of a 49-year-old woman with a parathyroid adenoma coexisting with two sites of papillary thyroid carcinoma. Dual-phase 99mTc-methoxyisobutylisonitrile (MIBI) parathyroid imaging before the operation correctly visualized the site of the parathyroid adenoma. In addition, two papillary thyroid carcinomas showed faint uptake of 99mTc-MIBI on delayed image. Total thyroidectomy and parathyroidectomy of a solitary parathyroid adenoma were performed. The patient subsequently underwent radioiodine-131 ablation and was treated with T4 suppression. This case illustrates the need for clinical awareness of concomitant hyperparathyroidism and thyroid cancer. Dual-phase 99mTc- MIBI parathyroid imaging may be useful for detecting indolent thyroid cancer before it becomes a distinct disease.

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