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Editorial
. 2009 Feb;84(2):105-7.
doi: 10.4065/84.2.105.

Targeting the pathogenic role of interleukin 1{beta} in the progression of smoldering/indolent myeloma to active disease

Charles A Dinarello
Editorial

Targeting the pathogenic role of interleukin 1{beta} in the progression of smoldering/indolent myeloma to active disease

Charles A Dinarello. Mayo Clin Proc. 2009 Feb.
No abstract available

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References

    1. Lust JA, Lacy MQ, Zeldenrust SR, et al. Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1β-induced interleukin-6 production and the myeloma proliferative component. Mayo Clin Proc. 2009;84(2): . - PMC - PubMed
    1. Kyle RA, Remstein ED, Therneau TM, et al. Clinical course and prognosis of smoldering (asymptomatic) multiple myeloma. N Engl J Med. 2007;356(25):2582-2590 - PubMed
    1. Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Ann Rev Immunol. 2009;27:519-550 - PubMed
    1. Voronov E, Shouval DS, Krelin Y, et al. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci U S A 2003March4;100(5):2645-2650 Epub 2003 Feb 21 - PMC - PubMed
    1. Lust JA, Donovan KA. The role of interleukin-1 beta in the pathogenesis of multiple myeloma. Hematol Oncol Clin North Am. 1999;13(6):1117-1125 - PubMed

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