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Review
. 2009 Feb;94(2):160-2.
doi: 10.3324/haematol.2008.004150.

T-cell acute lymphoblastic leukemia

Review

T-cell acute lymphoblastic leukemia

Sabina Chiaretti et al. Haematologica. 2009 Feb.

Abstract

The T-cell variant accounts for about 15 to 25% of acute lymphoblastic leukemias in children and adults. In this perspective article. Drs. Chiaretti and Foà examine our present understanding of this disorder. See related article on page 224.

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References

    1. Pui CH, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med. 2004;350:1535–48. - PubMed
    1. Ferrando AA, Neuberg DS, Staunton J, Loh ML, Huard C, Raimondi SC, et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell. 2002;1:75–87. - PubMed
    1. Bene MC, Castoldi G, Knapp W, Ludwig WD, Matutes E, Orfao A, et al. Proposals for the immunological classification of acute leukemias. European Group for the Immunological Characterization of Leukemias (EGIL) Leukemia. 1995;9:1783–6. - PubMed
    1. Fischer L, Gökbuget N, Schwartz S, Burmeister T, Rieder H, Brüggemann M, et al. CD56 expression in T-cell acute lymphoblastic leukemia is associated with non-thymic phenotype and resistance to induction therapy but no inferior survival after risk-adapted therapy. Haematologica. 2009;94:224–9. - PMC - PubMed
    1. Chiaretti S, Li X, Gentleman R, Vitale A, Vignetti M, Mandelli F, et al. Gene expression profile of adult T-cell acute lymphocytic leukemia identifies distinct subsets of patients with different response to therapy and survival. Blood. 2004;103:2771–8. - PubMed

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