Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1991 Sep:26 Suppl 5:7-13; discussion 52-4.
doi: 10.1080/21548331.1991.11707737.

Pharmacokinetics of ceftriaxone

J Blumer  1
Affiliations
Review

Pharmacokinetics of ceftriaxone

J Blumer. Hosp Pract (Off Ed). 1991 Sep.

Abstract

Ceftriaxone fulfills many of the qualities of an ideal antibiotic: a prolonged elimination half-life, which results from a "restrictive" excretion pattern; saturable protein binding, which provides the theoretical basis for administering the total daily dose as a single bolus; and once-a-day dosing, which provides plasma and tissue concentrations that exceed the MIC for most susceptible pathogens for 24 hours.

PubMed Disclaimer