Siderocalins: siderophore-binding proteins of the innate immune system
- PMID: 19184458
- DOI: 10.1007/s10534-009-9207-6
Siderocalins: siderophore-binding proteins of the innate immune system
Abstract
Recent studies have revealed that the mammalian immune system directly interferes with siderophore-mediated iron acquisition through siderophore-binding proteins and that the association of certain siderophores, or siderophore modifications, with virulence is a direct response of pathogens to evade these defenses.