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. 2009 Oct;36(10):1063-8.
doi: 10.1111/j.1600-0560.2008.01221.x. Epub 2009 Jan 27.

Melanocytic nevi with features of Spitz nevi and Clark's/dysplastic nevi ("Spark's" nevi)

Christine J Ko  1 , Jennifer M McNiff, Earl J Glusac
Affiliations

Melanocytic nevi with features of Spitz nevi and Clark's/dysplastic nevi ("Spark's" nevi)

Christine J Ko et al. J Cutan Pathol. 2009 Oct.

Abstract

Background: Nevi with cytologic characteristics of Spitz nevus and architectural features of Clark's/dysplastic nevus are not well recognized in the literature.

Methods: Twenty-seven nevi with characteristics of Spitz nevus and Clark's/dysplastic nevus are reviewed.

Results: The patients' mean age was 33 years, and 17/27(63%) patients were female. Lesions were most frequent on the trunk and lower extremities. Histopathologically, these nevi were composed of large, monomorphous spindled and/or epithelioid melanocytes. Spindle cells were often oriented parallel to the epidermis, with fused rete and lamellar fibroplasias. Lateral extension of the junctional component was a feature of compound lesions. An average of 10 years of clinical follow up in 12 patients revealed no recurrence or metastasis.

Conclusions: Recognition of this type of nevus is important to avoid confusion with malignant melanoma.

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