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Review
. 2009 Feb;122(2 Suppl):S22-32.
doi: 10.1016/j.amjmed.2008.12.004.

Safety of bisphosphonates in the treatment of osteoporosis

Robert R Recker  1 , E Michael Lewiecki, Paul D Miller, James Reiffel
Affiliations
Review

Safety of bisphosphonates in the treatment of osteoporosis

Robert R Recker et al. Am J Med. 2009 Feb.

Abstract

In this review 4 experts consider the major safety concerns relating to bisphosphonate therapy for osteoporosis. Specific topics covered are skeletal safety (particularly with respect to atypical fractures and delayed healing), gastrointestinal intolerance, hypocalcemia, acute-phase (i.e., postdose) reactions, chronic musculoskeletal pain, renal safety, and cardiovascular safety (specifically, atrial fibrillation).

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