Retroperitoneal lymph nodes in transitional cell carcinoma of the kidney and ureter
- PMID: 19190765
- PMCID: PMC2630418
- DOI: 10.1155/2009/181927
Retroperitoneal lymph nodes in transitional cell carcinoma of the kidney and ureter
Abstract
The incidence of transitional cell carcinoma of the kidney and ureter is low and for that reason limited data exists regarding the appropriate management of regional retroperitoneal lymph nodes. Lymph node metastases have consistently been associated with an adverse prognosis. However, five-year cancer-specific survival following nephroureterectomy and lymphadenectomy for patients with lymph node involvement ranges from 0-39%, suggesting a therapeutic benefit. This review covers the primary tumor characteristics associated with lymph node involvement, imaging of the lymph nodes, as well as the rationale, role, patient selection, suggested anatomic templates, and technical considerations for lymphadenectomy.
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References
-
- American Cancer Society. Cancer Facts & Figures 2007. Atlanta, Ga, USA: American Cancer Society; 2007.
-
- Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA: A Cancer Journal for Clinicians. 2005;55(1):10–30. - PubMed
-
- Huben RP, Mounzer AM, Murphy GP. Tumor grade and stage as prognostic variables in upper tract urothelial tumors. Cancer. 1988;62(9):2016–2020. - PubMed
-
- Herr HW, Donat SM. Outcome of patients with grossly node positive bladder cancer after pelvic lymph node dissection and radical cystectomy. The Journal of Urology. 2001;165(1):62–64. - PubMed
-
- Lerner SP, Skinner DG, Lieskovsky G, et al. The rationale for en bloc pelvic lymph node dissection for bladder cancer patients with nodal metastases: long-term results. The Journal of Urology. 1993;149(4):758–765. - PubMed
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