Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2009 Feb 4;28(3):167-8.
doi: 10.1038/emboj.2008.292.

Targeting a chronic problem: elimination of cancer stem cells in CML

Claus Nerlov  1
Affiliations
Comment

Targeting a chronic problem: elimination of cancer stem cells in CML

Claus Nerlov. EMBO J. .
No abstract available

PubMed Disclaimer

Comment on

  • Cancer induction by restriction of oncogene expression to the stem cell compartment.
    Pérez-Caro M, Cobaleda C, González-Herrero I, Vicente-Dueñas C, Bermejo-Rodríguez C, Sánchez-Beato M, Orfao A, Pintado B, Flores T, Sánchez-Martín M, Jiménez R, Piris MA, Sánchez-García I. Pérez-Caro M, et al. EMBO J. 2009 Jan 7;28(1):8-20. doi: 10.1038/emboj.2008.253. Epub 2008 Nov 27. EMBO J. 2009. PMID: 19037256 Free PMC article.

References

    1. Bonnet D, Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730–737 - PubMed
    1. Cho RW, Clarke MF (2008) Recent advances in cancer stem cells. Curr Opin Genet Dev 18: 48–53 - PubMed
    1. Graham SM, Jorgensen HG, Allan E, Pearson C, Alcorn MJ, Richmond L, Holyoake TL (2002) Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 99: 319–325 - PubMed
    1. Jamieson CH, Ailles LE, Dylla SJ, Muijtjens M, Jones C, Zehnder JL, Gotlib J, Li K, Manz MG, Keating A, Sawyers CL, Weissman IL (2004) Granulocyte–macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 351: 657–667 - PubMed
    1. Jorgensen HG, Holyoake TL (2007) Characterization of cancer stem cells in chronic myeloid leukaemia. Biochem Soc Trans 35 (Part 5): 1347–1351 - PubMed