doi: 10.1166/jnn.2008.482.
DNA-directed self-assembly of fluorescent dye-labeled streptavidin arrays for protein detection
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- PMID: 19198345
- DOI: 10.1166/jnn.2008.482
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DNA-directed self-assembly of fluorescent dye-labeled streptavidin arrays for protein detection
J Nanosci Nanotechnol.
2008 Nov.
Abstract
In this work, a DNA lattice was utilized to direct protein self-assembly. A model biosensor system was fabricated by self-assembly of rhodamine dye-labeled streptavidin molecules on a two-tile DNA system. This self-assembly nanofabrication technique has numerous possible biotechnology applications, including use in multiplex biosensing systems that have binding of several biological molecules encoded in a multiple-tile DNA lattice.
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