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Comment
. 2009 Feb 6;4(2):100-2.
doi: 10.1016/j.stem.2009.01.003.

The river of stem cells

Cheng-Ming Chuong  1 , Randall Bruce Widelitz
Affiliations
Comment

The river of stem cells

Cheng-Ming Chuong et al. Cell Stem Cell. .

Abstract

In this issue of Cell Stem Cell, Greco et al. (2009) characterize the hair germ as a novel stop between bulge stem cell and transient amplifying cells during hair regeneration. The work implies stem cell states can be regulated to form different numbers of intermediate stops, depending on physiological requirements.

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Figures

Figure 1
Figure 1. Landscape Concept of Stem Cell “Rivers”
Stem cells progress toward differentiation states via different modes or routes. Intermediate stops may be added or omitted, depending on the topology of different ectodermal organs and physiological needs. Orange particles in the “river” represent cells.
See this image and copyright information in PMC

Comment on

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