Multi-modal imaging in epilepsy: SPECT and PET
- PMID: 19203001
Multi-modal imaging in epilepsy: SPECT and PET
Abstract
SPECT and PET play a complementary role in the presurgical evaluation of patients with refractory epilepsy. Perfusion SPECT can identify the ictal onset zone and PET can delineate the functional deficit zone. Both modalities have a role in localization and characterization of the epileptic focus and can help in the guidance of invasive EEG and in detecting subtle lesions on MRI.
Similar articles
-
Neuronuclear assessment of patients with epilepsy.Semin Nucl Med. 2008 Jul;38(4):227-39. doi: 10.1053/j.semnuclmed.2008.02.004. Semin Nucl Med. 2008. PMID: 18514079 Review.
-
PET/MRI and PET/MRI/SISCOM coregistration in the presurgical evaluation of refractory focal epilepsy.Epilepsy Res. 2015 Mar;111:1-9. doi: 10.1016/j.eplepsyres.2014.12.011. Epub 2015 Jan 3. Epilepsy Res. 2015. PMID: 25769367
-
Perfusion SPECT, SISCOM and PET (18)F-FDG in the assessment of drug- refractory epilepsy patients candidates for epilepsy surgery.Rev Esp Med Nucl Imagen Mol. 2015 Nov-Dec;34(6):350-7. doi: 10.1016/j.remn.2015.05.002. Epub 2015 Jun 26. Rev Esp Med Nucl Imagen Mol. 2015. PMID: 26118354 English, Spanish.
-
Utility of gray-matter segmentation of ictal-Interictal perfusion SPECT and interictal 18F-FDG-PET in medically refractory epilepsy.Epilepsy Res. 2017 Feb;130:93-100. doi: 10.1016/j.eplepsyres.2017.01.009. Epub 2017 Jan 30. Epilepsy Res. 2017. PMID: 28171851
-
The use of SPECT and PET in routine clinical practice in epilepsy.Curr Opin Neurol. 2007 Apr;20(2):194-202. doi: 10.1097/WCO.0b013e328042baf6. Curr Opin Neurol. 2007. PMID: 17351491 Review.
Cited by
-
On the optimal z-score threshold for SISCOM analysis to localize the ictal onset zone.EJNMMI Res. 2018 Apr 17;8(1):34. doi: 10.1186/s13550-018-0381-9. EJNMMI Res. 2018. PMID: 29667074 Free PMC article.
-
Clinical Usefulness of SISCOM-SPM Compared to Visual Analysis to Locate the Epileptogenic Zone.Front Neurol. 2020 May 29;11:467. doi: 10.3389/fneur.2020.00467. eCollection 2020. Front Neurol. 2020. PMID: 32547479 Free PMC article.
-
Quantitative SISCOM assessment for epileptogenic zone localization: insights from a multicenter study comparing two software platforms in temporal lobe epilepsy.Front Neurol. 2025 Apr 15;16:1552774. doi: 10.3389/fneur.2025.1552774. eCollection 2025. Front Neurol. 2025. PMID: 40303886 Free PMC article.