Elongator bridges tubulin acetylation and neuronal migration
- PMID: 19203572
- DOI: 10.1016/j.cell.2009.01.024
Elongator bridges tubulin acetylation and neuronal migration
Abstract
Neuronal cell migration and maturation are crucial for the development of the mammalian cerebral cortex. In this issue, Creppe et al. (2009) now show that the multisubunit histone acetyltransferase Elongator may regulate migration and branch formation of cortical neurons in the developing mouse brain by acetylating alpha-tubulin.
Comment on
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Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.Cell. 2009 Feb 6;136(3):551-64. doi: 10.1016/j.cell.2008.11.043. Epub 2009 Jan 29. Cell. 2009. PMID: 19185337
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