High mortality among patients with AIDS who received a diagnosis of tuberculosis in the first 3 months of antiretroviral therapy
- PMID: 19207078
- PMCID: PMC3010922
- DOI: 10.1086/597098
High mortality among patients with AIDS who received a diagnosis of tuberculosis in the first 3 months of antiretroviral therapy
Abstract
We analyzed mortality among 201 patients with AIDS and tuberculosis in Haiti. Patients who received a diagnosis of tuberculosis during the first 3 months after the initiation of antiretroviral therapy were 3.25 times more likely to die than were other patients with AIDS and tuberculosis. Failure to recognize active tuberculosis at initiation of antiretroviral therapy leads to increased mortality.
Conflict of interest statement
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Comment in
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Reducing the burden of tuberculosis presenting during the initial months of antiretroviral therapy in resource-limited settings.Clin Infect Dis. 2010 Jan 1;50(1):124-5; author reply 125. doi: 10.1086/649007. Clin Infect Dis. 2010. PMID: 20001527 Free PMC article. No abstract available.
References
-
- Lawn SD, Myer L, Bekker LG, Wood R. Burden of tuberculosis in an antiretroviral treatment programme in sub-Saharan Africa: impact on treatment outcomes and implications for tuberculosis control. AIDS. 2006;20:1605–12. - PubMed
-
- Bonnet MM, Pinoges LL, Varaine FF, et al. Tuberculosis after HAART initiation in HIV-positive patients from five countries with a high tuberculosis burden. AIDS. 2006;20:1275–9. - PubMed
-
- Getahun H, Harrington M, O’Brien R, Nunn P. Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resource-constrained settings: informing urgent policy changes. Lancet. 2007;369:2042–9. - PubMed
-
- World Health Organization. Core Health Indicators. Geneva: World Health Organization; 2007.
-
- World Health Organization. Antiretroviral therapy for HIV infection in adults and adolescents in resource-limited settings: towards universal access: recommendations for a public health approach. Geneva: World Health Organization; 2006.
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