Selfish DNA: homing endonucleases find a home
- PMID: 19211047
- DOI: 10.1016/j.cub.2008.12.019
Selfish DNA: homing endonucleases find a home
Abstract
Self-splicing group I introns come in two flavours - those with a homing endonuclease to promote mobility of the intron, and those without an endonuclease. How homing endonucleases and self-splicing introns associate to form a composite selfish genetic element is a question of long-standing interest. Recent work has revealed that a shared characteristic of both introns and endonucleases, the targeting of conserved sequences, may provide the impetus for the evolution of composite mobile genetic elements.
Similar articles
-
A free-standing homing endonuclease targets an intron insertion site in the psbA gene of cyanophages.Curr Biol. 2009 Feb 10;19(3):218-22. doi: 10.1016/j.cub.2008.11.069. Curr Biol. 2009. PMID: 19200728
-
The recent transfer of a homing endonuclease gene.Nucleic Acids Res. 2005 May 12;33(8):2734-41. doi: 10.1093/nar/gki564. Print 2005. Nucleic Acids Res. 2005. PMID: 15891115 Free PMC article.
-
Characterization of the I-Spom I endonuclease from fission yeast: insights into the evolution of a group I intron-encoded homing endonuclease.J Mol Evol. 2002 Sep;55(3):302-13. doi: 10.1007/s00239-001-2327-4. J Mol Evol. 2002. PMID: 12187383
-
Homing endonuclease structure and function.Q Rev Biophys. 2005 Feb;38(1):49-95. doi: 10.1017/S0033583505004063. Epub 2005 Dec 9. Q Rev Biophys. 2005. PMID: 16336743 Review.
-
Invasion of a multitude of genetic niches by mobile endonuclease genes.FEMS Microbiol Lett. 2000 Apr 15;185(2):99-107. doi: 10.1111/j.1574-6968.2000.tb09046.x. FEMS Microbiol Lett. 2000. PMID: 10754232 Review.
Cited by
-
Group I introns and inteins: disparate origins but convergent parasitic strategies.J Bacteriol. 2009 Oct;191(20):6193-202. doi: 10.1128/JB.00675-09. Epub 2009 Aug 7. J Bacteriol. 2009. PMID: 19666710 Free PMC article. Review. No abstract available.
-
Isolation and Characterization of Phages Active against Paenibacillus larvae Causing American Foulbrood in Honeybees in Poland.Viruses. 2021 Jun 23;13(7):1217. doi: 10.3390/v13071217. Viruses. 2021. PMID: 34201873 Free PMC article.
-
The evolutionary history of Saccharomyces species inferred from completed mitochondrial genomes and revision in the 'yeast mitochondrial genetic code'.DNA Res. 2017 Dec 1;24(6):571-583. doi: 10.1093/dnares/dsx026. DNA Res. 2017. PMID: 28992063 Free PMC article.
-
Novel Freshwater Cyanophages Provide New Insights into Evolutionary Relationships between Freshwater and Marine Cyanophages.Microbiol Spectr. 2021 Oct 31;9(2):e0059321. doi: 10.1128/Spectrum.00593-21. Epub 2021 Sep 29. Microbiol Spectr. 2021. PMID: 34585945 Free PMC article.
-
Conditional Split Inteins: Adaptable Tools for Programming Protein Functions.Int J Mol Sci. 2025 Jan 11;26(2):586. doi: 10.3390/ijms26020586. Int J Mol Sci. 2025. PMID: 39859302 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases