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Comment
. 2009 Feb 12;457(7231):801-3.
doi: 10.1038/457801a.

Developmental biology: Birth of the blood cell

Momoko Yoshimoto, Mervin C Yoder
Comment

Developmental biology: Birth of the blood cell

Momoko Yoshimoto et al. Nature. .

Abstract

Could it be that fetal liver cells and adult bone-marrow cells originate from a subset of endothelial cells that line blood vessels in the mouse embryo? Several lines of evidence suggest that this might be the case.

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Figures

Figure 1
Figure 1
Relationship between endothelial cells and blood cells. Endothelial cells line the inside of blood vessels. During mouse embryonic development, a subset of these cells, known as haemogenic endothelial cells, seems to give rise to haematopoietic stem cells (HSCs) and their progenitors, such as those that seed the fetal liver and the adult bone marrow.–
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Comment on

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