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Review
. 2009 Feb 19;5(2):109-11.
doi: 10.1016/j.chom.2009.01.007.

Mammalian PGRPs in the spotlight

Ivo Gomperts Boneca  1
Affiliations
Free article
Review

Mammalian PGRPs in the spotlight

Ivo Gomperts Boneca. Cell Host Microbe. .
Free article

Abstract

Peptidoglycan-recognition proteins (PGRPs) play a central role in the insect innate immune response to bacteria. In this issue of Cell Host & Microbe, Saha et al. (2009) report that the mammalian PGRP, PGLYRP-2, functions as a cytokine-like molecule in a PG-induced arthritis model.

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