A mark of silence in malaria parasites
- PMID: 19218082
- DOI: 10.1016/j.chom.2009.01.006
A mark of silence in malaria parasites
Abstract
Gene families in malaria parasites that encode hypervariable surface antigens display mutually exclusive expression that is controlled epigenetically. In this issue, Lopez-Rubio et al. (2009) show that the histone mark H3K9me3 is specifically associated with regulation of expression of these gene families within repressive centers located at the nuclear periphery.
Comment on
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Genome-wide analysis of heterochromatin associates clonally variant gene regulation with perinuclear repressive centers in malaria parasites.Cell Host Microbe. 2009 Feb 19;5(2):179-90. doi: 10.1016/j.chom.2008.12.012. Cell Host Microbe. 2009. PMID: 19218088
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