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. 2009 Apr;99(4):690-7.
doi: 10.2105/AJPH.2007.128843. Epub 2009 Feb 12.

Contribution of race/ethnicity and country of origin to variations in lifetime reported asthma: evidence for a nativity advantage

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Contribution of race/ethnicity and country of origin to variations in lifetime reported asthma: evidence for a nativity advantage

S V Subramanian et al. Am J Public Health. 2009 Apr.

Abstract

Objectives: We assessed the relative contribution of Hispanic ethnicity, country of origin, and nativity to lifetime prevalence of asthma among mothers and children enrolled in the Project on Human Development in Chicago Neighborhoods.

Methods: We used multilevel models to analyze data from wave 3 of the Project on Human Development in Chicago Neighborhoods study (2000 to 2001). Mothers reported physician-diagnosed asthma for themselves and their children. Maternal race, ethnicity, country of origin, and nativity were the predictors of interest.

Results: We found substantial heterogeneity in lifetime asthma within Hispanic subgroups for mothers and children. Hispanics of non-Mexican origin had greater odds of having asthma than did non-Hispanic Whites; respondents of Mexican origin did not differ from non-Hispanic Whites. Odds of experiencing asthma were more strongly related to nativity than to race, Hispanic ethnicity, or country of origin. Only immigrant Mexicans reported asthma prevalence lower than that of native non-Hispanic Whites.

Conclusions: Nativity is a strong predictor of lifetime asthma prevalence, suggesting the importance of potential interactions between genetic susceptibilities and environmental factors in both the native and the host countries.

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Figures

FIGURE 1
FIGURE 1
Odds ratios and 95% confidence intervals for lifetime reported asthma among mothers and children, by race/ethnicity: Project on Human Development in Chicago Neighborhoods, 2000–2001. Note. The results reflect adjustment for age (centered by mean age), marital status, mother's education, household equivalized income, mother's smoking status, and place of birth. Models predicting child's asthma were further adjusted for gender, maternal history of asthma, and breastfeeding.
FIGURE 2
FIGURE 2
Odds ratios and 95% confidence intervals for lifetime reported asthma among mothers and children, by nativity: Project on Human Development in Chicago Neighborhoods, 2000–2001. Note. The results reflect adjustment for age (centered by mean age), marital status, mother's education, household equivalized income, mother's smoking status, and place of birth. Models predicting child's asthma were further adjusted for gender, maternal history of asthma, and breastfeeding.

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