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Review
. 2008;29(6-8):159-62.
doi: 10.1007/s10974-009-9169-x. Epub 2009 Feb 14.

Myocardial adaptations in the failing heart: cause or consequence?

Sabine J van Dijk  1 , Nazha Hamdani, Ger J M Stienen, Jolanda van der Velden
Affiliations
Review

Myocardial adaptations in the failing heart: cause or consequence?

Sabine J van Dijk et al. J Muscle Res Cell Motil. 2008.

Abstract

Many changes in morphology, biochemical properties and myocyte function occur during development to heart failure. Most changes may be compensatory, yet unable to prevent cardiac dysfunction in the long run. This illustrates that it is important to carefully dissect the disease causing modifications from cardiac adaptation, in order to obtain a better understanding of the pathophysiological processes leading to heart failure.

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