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Case Reports
. 2009 Feb 16;190(4):210-1.
doi: 10.5694/j.1326-5377.2009.tb02353.x.

Ocular pigmentation associated with clozapine

Armand M Borovik  1 , Martina M Bosch, Stephanie L Watson
Affiliations
Case Reports

Ocular pigmentation associated with clozapine

Armand M Borovik et al. Med J Aust. .

Abstract

A 55-year-old woman who was treated with long-term, high-dose clozapine for schizophrenia presented with bilateral decreased visual acuity. She had pigmentary changes affecting the cornea and the retina, as well as stellate cataract. Chlorpromazine use is known to produce similar changes, but this is the first report to our knowledge of pigmentation associated with clozapine use.

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