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. 1977 Mar 1;161(3):639-42.
doi: 10.1042/bj1610639.

Cholera toxin requires oxidized nicotinamide-adenine dinucleotide to activate adenylate cyclase in purified rat liver plasma membranes

B R Martin, M D Houslay, E L Kennedy

Cholera toxin requires oxidized nicotinamide-adenine dinucleotide to activate adenylate cyclase in purified rat liver plasma membranes

B R Martin et al. Biochem J. .

Abstract

Activation of adenylate cyclase in isolated rat liver plasma membranes by cholera toxin was demonstrated. The activation requires the presence of NAD+ and ATP and is irreversible.

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