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. 2009;15(13):3065-8.
doi: 10.1002/chem.200801847.

The double solubility rule holds for racemizing enantiomers

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The double solubility rule holds for racemizing enantiomers

Toshiko Izumi et al. Chemistry. 2009.

Abstract

Chiral amnesia: Experimental results demonstrate that the double solubility rule indeed holds true for the solution-phase enantiomers of a conglomerate-forming solid under fast-racemizing conditions. There is neither experimental evidence for chiral recognition via solution-phase clusters nor a need to invoke them to produce a lucid explanation of the compelling model for the evolution of solid-phase homochirality first communicated by Viedma.

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