Drug safety and the role of clinical pharmacology in the safe use of therapeutics

Editorial

P K Honig. Clin Pharmacol Ther. 2009 Mar.

. 2009 Mar;85(3):225-8.

doi: 10.1038/clpt.2008.275.

No abstract available

Comment on

Perspectives on early communication of drug risks to the public.
Seligman PJ, Osborne SF. Seligman PJ, et al. Clin Pharmacol Ther. 2009 Mar;85(3):335-9. doi: 10.1038/clpt.2008.272. Epub 2009 Jan 21. Clin Pharmacol Ther. 2009. PMID: 19158665 Review. No abstract available.

"Getting the dose right": facts, a blueprint, and encouragements.
Peck CC, Cross JT. Peck CC, et al. Clin Pharmacol Ther. 2007 Jul;82(1):12-4. doi: 10.1038/sj.clpt.6100215. Clin Pharmacol Ther. 2007. PMID: 17571068 No abstract available.
Metabolites in safety testing: "MIST" for the clinical pharmacologist.
Frederick CB, Obach RS. Frederick CB, et al. Clin Pharmacol Ther. 2010 Mar;87(3):345-50. doi: 10.1038/clpt.2009.283. Epub 2010 Jan 27. Clin Pharmacol Ther. 2010. PMID: 20107437 Review. No abstract available.
Are single-dose toxicology studies in animals adequate to support single doses of a new drug in humans?
Monro A, Mehta D. Monro A, et al. Clin Pharmacol Ther. 1996 Mar;59(3):258-64. doi: 10.1016/S0009-9236(96)80002-6. Clin Pharmacol Ther. 1996. PMID: 8653987 No abstract available.
Food and Drug Administration's Safe Use Initiative collaborating to reduce preventable harm from medications.
U S Food And Drug Administration. U S Food And Drug Administration. J Pain Palliat Care Pharmacother. 2010 Mar;24(1):76-93. doi: 10.3109/15360280903583214. J Pain Palliat Care Pharmacother. 2010. PMID: 20345207 No abstract available.
Pharmacological mechanism-based drug safety assessment and prediction.
Abernethy DR, Woodcock J, Lesko LJ. Abernethy DR, et al. Clin Pharmacol Ther. 2011 Jun;89(6):793-7. doi: 10.1038/clpt.2011.55. Epub 2011 Apr 13. Clin Pharmacol Ther. 2011. PMID: 21490594 Review.